Below are a list of known affixes which can be found on bosses in Diablo 4. This list is based on the Diablo 4 beta and there may be more come final release.
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| Name | Effect | |
|---|---|---|
| Chaos | ||
| Chilling Wind | Chills the player with an icy wind. | |
| Cold Enchanted | Shots from enemy will chill you when hit. | |
| Shock Lance | Orb of Lightning that rotates with single lightning lance. | |
| Fire Enchanted | Shoots out fireballs randomly. | |
| Fire Orbs | ||
| Frozen | Fires three ice crystals on the ground chilling players. They will also explode. | |
| Lightning Enchanted | Arc of lightning released by monster when monster is hit. | |
| Mortar | Spits out fire shots that propel upwards and then land. | |
| Multishot | Shots fired by monsters split into three instead of one. | |
| Plaguebearer | Pool of poison appears and explodes under monster on death. | |
| Poison Enchanted | Pool of poison materialises under the player. Pool also appears under monster on monster's death. | |
| Shadow Enchanted | A copy of the monster materialises attacking player before dissappearing. | |
| Summoner | Summons two weaker minions to fight the player. | |
| Suppressor | Protective shield surrounds the monster protecting it from ranged and magic attacks. | |
| Teleporter | Teleports around the area making it hard to hit. | |
| Hellbound | Summons a statue with chains that holds the player in place for a short period of time. | |
| Vampiric Enrage | Drains health from player with monster benefitting from the health drained. | |
| Terrifying | This is Fear, two pentagrams will make the player flee for a few seconds. | |
| Waller | Creates a wall to block the player in. The wall will only cover 3 sides allowing the player to escape. |